Pre-treatment tumour PET metrics and clinical outcomes of anal cancer in patients living with and without HIV

Outcomes were comparable between HIV-negative patients and PLWH. Pre-treatment PET metrics were validated as significantly predicting outcomes for the entire cohort and HIV-negative patients, not PLWH. This may be from small numbers of PLWH patients, or non-specific uptake in patients with uncontrolled HIV reducing PET's prognostic efficacy.

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Publication Details

Journal
Acta Oncologica
Published
2025-04-24
DOI
https://doi.org/10.2340/1651-226x.2025.40680
Primary Topic
Colorectal and Anal Carcinomas
Type
article
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article

Pre-treatment tumour PET metrics and clinical outcomes of anal cancer in patients living with and without HIV

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Pre-treatment tumour PET metrics and clinical outcomes of anal cancer in patients living with and without HIV

Shalom Kalnicki, Wolfgang A. Tomé, Megi Gjini, Christian Velten, N. Patrik Brodin, Nitin Ohri, Chandan Guha, Rafi Kabarriti, Michael Pennock, Madhur Garg
article en

Abstract

Outcomes were comparable between HIV-negative patients and PLWH. Pre-treatment PET metrics were validated as significantly predicting outcomes for the entire cohort and HIV-negative patients, not PLWH. This may be from small numbers of PLWH patients, or non-specific uptake in patients with uncontrolled HIV reducing PET's prognostic efficacy.

Acta OncologicaVol. 64
Montefiore Medical Center (US)
Good health and well-being
Openalex Percentile: Top 85%
Colorectal and Anal Carcinomas
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