Development of an Adjustable Arm‐Type Swept‐Source Optical Coherence Tomography System for Pediatric Patients With Congenital Cataracts

We developed a stable, high-penetration arm-type swept-source optical coherence tomography (SS-OCT) system for visualizing retinal and choroidal structures in pediatric patients with congenital cataracts. The system features a compact OCT probe with an integrated iris camera and fixation target for easy alignment, mounted on a five-degree-of-freedom adjustable arm to reduce motion artifacts and operator fatigue. Feasibility was demonstrated through supine retinal imaging of healthy adults, congenital cataract children, and infants, achieving success rates of 100%, 97%, and 95%, respectively. The system captured abnormal retinal features (e.g., absent foveal structure) in congenital cataract patients, highlighting its clinical value for monitoring retinal development. High-speed (200 kHz) imaging and high-resolution (4.1 μm) further support its dual role in clinical diagnosis and scientific research, such as retinal development studies and visual prognosis modeling. This system demonstrates significant potential for routine use in clinical practice and research, offering a reliable tool for pediatric ophthalmic imaging.

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Publication Details

Journal
Journal of Biophotonics
Published
2025-04-24
DOI
https://doi.org/10.1002/jbio.70039
Primary Topic
Optical Coherence Tomography Applications
Type
article
Field-Weighted Citation Impact
0.00

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article

Development of an Adjustable Arm‐Type Swept‐Source Optical Coherence Tomography System for Pediatric Patients With Congenital Cataracts

Sisi Chen, Zhangliang Li, Meixiao Shen, Yun‐e Zhao et al.
Journal of Biophotonics
Optical Coherence Tomography Applications
article

Development of an Adjustable Arm‐Type Swept‐Source Optical Coherence Tomography System for Pediatric Patients With Congenital Cataracts

Sisi Chen, Zhangliang Li, Meixiao Shen, Yun‐e Zhao, Shi-Lei Wang, Peifeng Zhang, Yutao Lan, Yue Jin, W. Su, Fan Lü, Wuge Shama
article en

Abstract

We developed a stable, high-penetration arm-type swept-source optical coherence tomography (SS-OCT) system for visualizing retinal and choroidal structures in pediatric patients with congenital cataracts. The system features a compact OCT probe with an integrated iris camera and fixation target for easy alignment, mounted on a five-degree-of-freedom adjustable arm to reduce motion artifacts and operator fatigue. Feasibility was demonstrated through supine retinal imaging of healthy adults, congenital cataract children, and infants, achieving success rates of 100%, 97%, and 95%, respectively. The system captured abnormal retinal features (e.g., absent foveal structure) in congenital cataract patients, highlighting its clinical value for monitoring retinal development. High-speed (200 kHz) imaging and high-resolution (4.1 μm) further support its dual role in clinical diagnosis and scientific research, such as retinal development studies and visual prognosis modeling. This system demonstrates significant potential for routine use in clinical practice and research, offering a reliable tool for pediatric ophthalmic imaging.

Journal of BiophotonicsVol. 18(9)
Wenzhou Medical University (CN), Affiliated Eye Hospital of Wenzhou Medical College (CN)
National Natural Science Foundation of China
Peace, Justice and strong institutions
Openalex Percentile: Top 92%
Optical Coherence Tomography Applications
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