Chiari 1.5 malformation: a case report and review of literature

Chiari 1.5 malformation, a rare neurological disorder, involves cerebellar tonsil herniation and slight brainstem descent through the foramen magnum. A 25-year-old woman presented with recurrent headaches exacerbated by coughing, straining, and difficulty in maintaining head posture despite normal motor functions and reflexes. MRI revealed a Chiari 1.5 malformation with a 13.5 mm cerebellar tonsil herniation, minor brainstem descent, and C2-C3 vertebrae fusion. Suboccipital craniectomy with foramen magnum decompression significantly alleviated her symptoms. This case emphasizes the importance of recognizing Chiari 1.5 malformation as a cause of headaches in young adults and supports surgical intervention to prevent neurological decline. Although the aetiology is unknown, theories suggest a pressure differential between the cranial and spinal subarachnoid spaces during fetal development. Early diagnosis and posterior fossa decompression are crucial for symptom management and outcome improvement in CHIARI 1.5.

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Publication Details

Journal
International Journal of Advances in Medicine
Published
2025-04-24
DOI
https://doi.org/10.18203/2349-3933.ijam20251084
Primary Topic
Spinal Dysraphism and Malformations
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article
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article

Chiari 1.5 malformation: a case report and review of literature

Raghavendra Selvan, Nishant Pandey, M. Nandhini, S. Sijith Hrishikaanthan
International Journal of Advances in Medicine
Spinal Dysraphism and Malformations
article

Chiari 1.5 malformation: a case report and review of literature

Raghavendra Selvan, Nishant Pandey, M. Nandhini, S. Sijith Hrishikaanthan
article en

Abstract

Chiari 1.5 malformation, a rare neurological disorder, involves cerebellar tonsil herniation and slight brainstem descent through the foramen magnum. A 25-year-old woman presented with recurrent headaches exacerbated by coughing, straining, and difficulty in maintaining head posture despite normal motor functions and reflexes. MRI revealed a Chiari 1.5 malformation with a 13.5 mm cerebellar tonsil herniation, minor brainstem descent, and C2-C3 vertebrae fusion. Suboccipital craniectomy with foramen magnum decompression significantly alleviated her symptoms. This case emphasizes the importance of recognizing Chiari 1.5 malformation as a cause of headaches in young adults and supports surgical intervention to prevent neurological decline. Although the aetiology is unknown, theories suggest a pressure differential between the cranial and spinal subarachnoid spaces during fetal development. Early diagnosis and posterior fossa decompression are crucial for symptom management and outcome improvement in CHIARI 1.5.

International Journal of Advances in MedicineVol. 12(3)
Kanyakumari Government Medical College (IN)
Openalex Percentile: Top 88%
Spinal Dysraphism and Malformations
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