Norepinephrine promotes oxidative stress in vascular adventitial fibroblasts via PKC/NFκB-mediated NOX2 upregulation
NE promotes oxidative stress by α-receptor/PKC/NFκB-mediated NOX2 upregulation, which contributes to proliferation and migration of VAFs.
Authors
- Hongbiao Dong (ORCID: https://orcid.org/0000-0003-1244-0364)
- Jing-Xiao Wang
- Xiaoyu Xu (ORCID: https://orcid.org/0000-0002-0327-7369)
- Guo‐Qing Zhu (ORCID: https://orcid.org/0000-0002-3132-9592)
- Min Dai (ORCID: https://orcid.org/0000-0002-3755-7596)
- Yiming Wang (ORCID: https://orcid.org/0009-0006-5979-2825)
- Xiuzhen Li (ORCID: https://orcid.org/0000-0001-5124-3051)
Institutions
- Second Affiliated Hospital of Nanjing Medical University (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- Redox Report
- Published
- 2025-04-23
- DOI
- https://doi.org/10.1080/13510002.2025.2494314
- Citations
- 2
- Primary Topic
- Nitric Oxide and Endothelin Effects
- Type
- article
- Field-Weighted Citation Impact
- 2.33
Funders
- National Natural Science Foundation of China
- Medical Science and Technology Development Foundation, Nanjing Municipality Health Bureau