Successful Aspiration Thrombectomy for Cocaine‐Induced Right Coronary Artery Embolism Secondary to Left Ventricular Thrombus: A Case Report and Literature Review

Coronary embolism (CE) is a rare yet significant contributor to acute myocardial infarction (AMI), particularly in younger patients. We report a 42-year-old male who experienced an AMI following recent cocaine use. Investigations revealed a left ventricular apical thrombus, identified as the source of a distal embolus occluding the right coronary artery (RCA). Cocaine is known for its thrombogenic effects, promoting thrombus formation through mechanisms such as vasoconstriction and increased platelet aggregation. This unique situation highlights the critical interplay between cocaine use, left ventricular thrombus formation, and the resultant coronary artery embolism, contributing to myocardial ischemia. The patient underwent successful aspiration thrombectomy, restoring coronary blood flow without the need for stenting. This case underscores the importance of recognizing CE as a potential etiology of AMI, particularly in the context of substance abuse, advocating for heightened awareness among clinicians regarding the complexities of managing thromboembolic events.

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Journal
Clinical Case Reports
Published
2025-04-23
DOI
https://doi.org/10.1002/ccr3.70432
Primary Topic
Atrial Fibrillation Management and Outcomes
Type
article
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article

Successful Aspiration Thrombectomy for Cocaine‐Induced Right Coronary Artery Embolism Secondary to Left Ventricular Thrombus: A Case Report and Literature Review

Ahmad Nouri, Emile Doss, Abraam Rezkalla, Islam Rajab et al.
Clinical Case Reports
Atrial Fibrillation Management and Outcomes
article

Successful Aspiration Thrombectomy for Cocaine‐Induced Right Coronary Artery Embolism Secondary to Left Ventricular Thrombus: A Case Report and Literature Review

Ahmad Nouri, Emile Doss, Abraam Rezkalla, Islam Rajab, Fadi Hadya
article en

Abstract

Coronary embolism (CE) is a rare yet significant contributor to acute myocardial infarction (AMI), particularly in younger patients. We report a 42-year-old male who experienced an AMI following recent cocaine use. Investigations revealed a left ventricular apical thrombus, identified as the source of a distal embolus occluding the right coronary artery (RCA). Cocaine is known for its thrombogenic effects, promoting thrombus formation through mechanisms such as vasoconstriction and increased platelet aggregation. This unique situation highlights the critical interplay between cocaine use, left ventricular thrombus formation, and the resultant coronary artery embolism, contributing to myocardial ischemia. The patient underwent successful aspiration thrombectomy, restoring coronary blood flow without the need for stenting. This case underscores the importance of recognizing CE as a potential etiology of AMI, particularly in the context of substance abuse, advocating for heightened awareness among clinicians regarding the complexities of managing thromboembolic events.

Clinical Case ReportsVol. 13(5)
An-Najah National University (PS), St. Joseph’s University Medical Center (US)
Good health and well-being
Openalex Percentile: Top 85%
Atrial Fibrillation Management and Outcomes
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Successful Aspiration Thrombectomy for Cocaine‐Induced Right Coronary Artery Embolism Secondary to Left Ventricular Thrombus: A Case Report and Literature Review — Ahmad Nouri, Emile Doss, et al. · Clinical Case Reports (2025) | TGRS Research Map | TGRS