Valosin‐Containing Protein (VCP/p97) Mediates Neuroendocrine Differentiation in Prostate Cancer Cells Through Pim1 Signaling Inducing Autophagy

VCP drives NED in PCa cells through a complex interplay involving the Pim1 axis and autophagy pathways. These findings highlight the potential of targeting VCP/p97 and its associated mechanisms as therapeutic strategies to inhibit NED progression.

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Publication Details

Journal
The Prostate
Published
2025-04-23
DOI
https://doi.org/10.1002/pros.24900
Citations
1
Primary Topic
Endoplasmic Reticulum Stress and Disease
Type
article
Field-Weighted Citation Impact
1.15
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article

Valosin‐Containing Protein (VCP/p97) Mediates Neuroendocrine Differentiation in Prostate Cancer Cells Through Pim1 Signaling Inducing Autophagy

Ramesh Ummanni, K Sruthi
1 citations
The Prostate
Endoplasmic Reticulum Stress and Disease
1.15
article

Valosin‐Containing Protein (VCP/p97) Mediates Neuroendocrine Differentiation in Prostate Cancer Cells Through Pim1 Signaling Inducing Autophagy

Ramesh Ummanni, K Sruthi
article en
1 citations

Abstract

VCP drives NED in PCa cells through a complex interplay involving the Pim1 axis and autophagy pathways. These findings highlight the potential of targeting VCP/p97 and its associated mechanisms as therapeutic strategies to inhibit NED progression.

The ProstateVol. 85(10)
Indian Institute of Chemical Technology (IN), Academy of Scientific and Innovative Research (IN)
Good health and well-being
Openalex Percentile: Top 25%
Endoplasmic Reticulum Stress and Disease
1.15
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