Key gene screening and diagnostic model establishment for acute type a aortic dissection
This study identifies key molecular markers and pathways in ATAAD pathogenesis, emphasizing the role of immune dysregulation and extracellular matrix remodeling. The multi-omics diagnostic model provides a novel tool for early screening, potentially reducing mortality through timely intervention. These findings advance the understanding of aortic dissection mechanisms and offer actionable targets for future research and clinical applications.
Authors
- Weizhang Xiao (ORCID: https://orcid.org/0000-0003-0069-3735)
- Xiaoyu Qian (ORCID: https://orcid.org/0000-0001-6954-1022)
- Xuesong Zhang (ORCID: https://orcid.org/0000-0002-1934-5717)
- Zhi‐Ming Yu (ORCID: https://orcid.org/0000-0002-7186-2543)
- Qun Xue (ORCID: https://orcid.org/0000-0003-1011-1284)
- Yue Pan (ORCID: https://orcid.org/0009-0000-9458-7110)
Institutions
- Nantong University (CN)
- Affiliated Hospital of Nantong University (CN)
Publication Details
- Journal
- Frontiers in Genetics
- Published
- 2025-04-24
- DOI
- https://doi.org/10.3389/fgene.2025.1586880
- Primary Topic
- Aortic Disease and Treatment Approaches
- Type
- article
- Field-Weighted Citation Impact
- 0.00