Maternal benzo[a]pyrene exposure during critical gestational periods impairs offspring neurological development in rats: a mechanistic study of the Wnt/β-catenin signaling pathway
These results suggest that B[a]P exposed in mid-gestation pregnancy may lead to neurological damage in the offspring by downregulating the Wnt/β-catenin signaling pathway.
Authors
- Wen Sun (ORCID: https://orcid.org/0000-0002-8111-8865)
- Yuanbao Zhang
- Wenping Zhang (ORCID: https://orcid.org/0000-0002-3905-3332)
- Wenlin Bai (ORCID: https://orcid.org/0000-0001-8699-607X)
- Zhenlin Zhao
- Bo Nan (ORCID: https://orcid.org/0000-0002-6580-7273)
- Nan Zhang (ORCID: https://orcid.org/0009-0002-5501-6299)
- Yingying Zhang
- Yuanhao Wang (ORCID: https://orcid.org/0000-0001-9583-3539)
- Lijian Lei
- Jianjun Zhou (ORCID: https://orcid.org/0000-0002-0302-6850)
Institutions
- Tongji University (CN)
- North University of China (CN)
- Shanxi Medical University (CN)
- Office of Adolescent Health (US)
- Beijing Academy of Science and Technology (CN)
- Shenzhen Ruipuxun Academy for Stem Cell & Regenerative Medicine
- Taiyuan University of Technology (CN)
Publication Details
- Journal
- Frontiers in Behavioral Neuroscience
- Published
- 2025-04-24
- DOI
- https://doi.org/10.3389/fnbeh.2025.1571122
- Primary Topic
- Toxic Organic Pollutants Impact
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Science Foundation
- National Natural Science Foundation of China
- Shanxi Medical University