Performance of a Novel <i>Plasmodium falciparum</i> Rapid Diagnostic Test in Areas of Widespread <i>hrp2/3</i> Gene Deletion
The single-line, easy-to-interpret index malaria RDT outperforms conventional HRP2-only RDTs, making it a promising tool for enhancing malaria diagnosis in regions with high hrp2/3 deletion prevalence. Clinical Trial Registration. The study is registered on ClinicalTrials.gov ID NCT05286359.
Authors
- Rebecca Barney (ORCID: https://orcid.org/0000-0002-9851-6659)
- Gonzalo J. Domingo (ORCID: https://orcid.org/0000-0002-1004-4395)
- Nega Berhe (ORCID: https://orcid.org/0000-0001-6959-989X)
- Allison Golden (ORCID: https://orcid.org/0000-0001-6891-5176)
- Berhanu Erko (ORCID: https://orcid.org/0000-0003-1685-752X)
- Hannah Slater (ORCID: https://orcid.org/0000-0003-4291-7899)
- Greg T. Bizilj
- Lemu Golassa (ORCID: https://orcid.org/0000-0002-1216-8711)
- Xavier C. Ding (ORCID: https://orcid.org/0000-0001-8409-3678)
- Aynalem Mandefro
- Bacha Mekonen
- Gezahegn Solomon Alemayehu (ORCID: https://orcid.org/0000-0003-1460-5716)
- Yirgalem Gebrehiwot
- Geletta Tadele
- Jocelyn Farge
Institutions
- Program for Appropriate Technology in Health (US)
- Hawassa University (ET)
- Wollega University (ET)
- Ethiopian Public Health Institute (ET)
- Abbott (Spain) (ES)
- Abbott (Germany) (DE)
- Ethiopian Defence University (ET)
- Addis Ababa University (ET)
Publication Details
- Journal
- Clinical Infectious Diseases
- Published
- 2025-04-22
- DOI
- https://doi.org/10.1093/cid/ciaf212
- Citations
- 7
- Primary Topic
- Malaria Research and Control
- Type
- article
- Field-Weighted Citation Impact
- 13.15
Funders
- Bill and Melinda Gates Foundation
- Addis Ababa University