Development and validation of a semi-automated [13N]Ammonia preparation system for clinical research
This semi-automated module offers a practical, low-cost solution for [<sup>13</sup>N]ammonia production in clinical research. Its design reduces operator exposure, increases reproducibility, and provides performance comparable to commercial synthesizers at a fraction of the cost. The system addresses the needs of facilities with limited throughput and infrastructure and serves as an accessible alternative to fully automated systems.
Authors
- Amy L. Vāvere (ORCID: https://orcid.org/0009-0008-2011-8790)
- Victor Amador Diaz (ORCID: https://orcid.org/0000-0001-8621-2634)
- Matthew S. Brown (ORCID: https://orcid.org/0000-0003-0575-3696)
- Peter Hall (ORCID: https://orcid.org/0009-0006-5699-5483)
Institutions
- St. Jude Children's Research Hospital (US)
Publication Details
- Journal
- Applied Radiation and Isotopes
- Published
- 2025-04-24
- DOI
- https://doi.org/10.1016/j.apradiso.2025.111861
- Primary Topic
- Medical Imaging Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00