The Strain Properties of Korean and North American Chronic Wasting Disease Prions Are Indistinguishable
These invariant features are consistent with infection of SK and North American cervids by the same CWD prion strain. Our findings contribute to a developing picture where a single, dominant prion strain is responsible for contagious CWD transmission among North American and SK cervids. The stability and consistency of this established strain contrasts with the highly diverse and relatively unstable features of incipient prion strains causing novel emergent CWD infections in moose, reindeer, and red deer from Northern Europe.
Authors
- Bailey K. Webster
- Hoo‐Chang Park
- Jifeng Bian (ORCID: https://orcid.org/0000-0001-6838-9938)
- Glenn C. Telling (ORCID: https://orcid.org/0000-0002-6294-1805)
- Hae‐Eun Kang (ORCID: https://orcid.org/0000-0002-6013-484X)
- Kyung Je Park
- Jenna Crowell (ORCID: https://orcid.org/0009-0009-9515-1023)
- Sehun Kim (ORCID: https://orcid.org/0000-0002-2637-9229)
- Joseph P. DeFranco (ORCID: https://orcid.org/0000-0003-3194-2677)
- Hyun Joo Sohn
Institutions
- Animal and Plant Quarantine Agency (KR)
- Colorado State University (US)
Publication Details
- Journal
- The Journal of Infectious Diseases
- Published
- 2025-04-23
- DOI
- https://doi.org/10.1093/infdis/jiaf210
- Citations
- 2
- Primary Topic
- Prion Diseases and Protein Misfolding
- Type
- article
- Field-Weighted Citation Impact
- 1.61