A case report of gallbladder adenomyomatosis and acute gangrenous cholecystitis: A causal or coincidental relationship?

Gallbladder adenomyomatosis (GA) is a benign, acquired pathology of the gallbladder, typically characterized by a favorable prognosis. While patients with GA are generally asymptomatic, nonspecific abdominal pain localized to the right upper quadrant and epigastrium is the most frequently reported symptom. We herein present a case of diffuse gallbladder adenomyomatosis that presented as acalculous cholecystitis, characterized by right upper quadrant pain, fever, and elevated inflammatory markers. Although ultrasound and CT scan did not reveal any radiological abnormalities at initial presentation, a subsequent MRCP confirmed the presence of diffuse gallbladder adenomyomatosis. • Gallbladder adenomyomatosis has the potential to mimic malignant lesions on radiological imaging, thereby posing a diagnostic challenge, given that the therapeutic approaches and prognostic implications for these two conditions are markedly different. • This article discusses a case of diffuse gallbladder adenomyomatosis that presented as acalculous cholecystitis, characterized by right upper quadrant pain, fever, and elevated inflammatory markers, despite both ultrasound and CT scans revealing no radiological abnormalities at presentation. • Subsequent MRCP confirmed the presence of diffuse gallbladder adenomyomatosis.