Liquid biopsy-derived extracellular vesicle protein biomarkers for diagnosis and prognostic assessment of lung squamous cell carcinoma
The novel nanomaterial NaY effectively enriches EVs from plasma. Utilizing plasma EV biomarkers, the diagnostic model demonstrates strong discriminative ability between benign and malignant pulmonary nodules in patients.
Authors
- Shujun Cheng (ORCID: https://orcid.org/0000-0001-5672-8461)
- Ruiqi Zheng
- Na Zhao (ORCID: https://orcid.org/0000-0001-9523-6072)
- Xin Dong
- Yutao Liu (ORCID: https://orcid.org/0000-0001-6477-9875)
- Jie Li (ORCID: https://orcid.org/0000-0003-4400-2131)
- Yaru Wang (ORCID: https://orcid.org/0000-0001-8698-081X)
- Ting Xiao (ORCID: https://orcid.org/0000-0002-5319-3411)
- Lei Song (ORCID: https://orcid.org/0000-0002-0162-4945)
- Sheng Ma (ORCID: https://orcid.org/0000-0002-7533-3892)
- Congcong Ma (ORCID: https://orcid.org/0009-0003-6003-8289)
- Xiao Zhi
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- National Cancer Center (US)
- Tianjin Medical University (CN)
Publication Details
- Journal
- Cancer Cell International
- Published
- 2025-04-24
- DOI
- https://doi.org/10.1186/s12935-025-03792-0
- Citations
- 2
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 1.61
Funders
- National Natural Science Foundation of China
- National Key Research and Development Program of China