Effects of IV Fluid Restriction According to Standard Fluid Treatment Intensity Across Conservative Versus Liberal Approach to Fluid Therapy of Septic Shock in Intensive Care (CLASSIC) Trial Sites
Among adult ICU patients with septic shock, variation in standard IV fluid volumes across sites did not substantially impact the effects of fluid restriction on outcomes after accounting for patient characteristics.
Authors
- Anders Perner (ORCID: https://orcid.org/0000-0002-4668-0123)
- Jon Henrik Laake (ORCID: https://orcid.org/0000-0001-6157-5359)
- Marek Nalos (ORCID: https://orcid.org/0000-0002-7977-9410)
- Morten Hylander Møller (ORCID: https://orcid.org/0000-0002-6378-9673)
- Manu L. N. G. Malbrain (ORCID: https://orcid.org/0000-0002-1816-5255)
- Benjamin Skov Kaas‐Hansen (ORCID: https://orcid.org/0000-0003-1023-0371)
- Stephan M. Jakob (ORCID: https://orcid.org/0000-0002-2195-0473)
- Peter Buhl Hjortrup (ORCID: https://orcid.org/0000-0002-3847-3247)
- Marlies Ostermann (ORCID: https://orcid.org/0000-0001-9500-9080)
- Tine Sylvest Meyhoff (ORCID: https://orcid.org/0000-0002-1840-1596)
- Anders Granholm (ORCID: https://orcid.org/0000-0001-5799-7655)
- Maria Cronhjort (ORCID: https://orcid.org/0000-0002-0444-8553)
- Praleene Sivapalan (ORCID: https://orcid.org/0000-0002-0442-0032)
- Maj-Brit N. Kjær
- Maurizio Cecconi (ORCID: https://orcid.org/0000-0002-4376-6538)
Institutions
- University of Bern (CH)
- Medical University of Lublin (PL)
- University of Copenhagen (DK)
- Oslo University Hospital (NO)
- St Thomas' Hospital (GB)
- Humanitas University (IT)
- Copenhagen University Hospital (DK)
- Rigshospitalet (DK)
- Karolinska Institutet (SE)
- Pilsen Tools (Czechia) (CZ)
- Centre for Research in Intensive Care (DK)
- St. Thomas Hospital (CA)
- Lillebaelt Hospital (DK)
- IRCCS Humanitas Research Hospital (IT)
Publication Details
- Journal
- Critical Care Medicine
- Published
- 2025-04-24
- DOI
- https://doi.org/10.1097/ccm.0000000000006679
- Citations
- 2
- Primary Topic
- Sepsis Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 2.71