[Electroacupuncture improves synaptic plasticity and cognitive dysfunction via down-regulating HDAC3 in mice of Alzheimer's disease].
EA of GV20 and GV14 can restore the impaired LTP and improve the cognitive impairment, which may be related to increasing the expressions of NMDA-related receptor proteins and down-regulating the expression of HDAC3 in the hippocampus of 5XFAD mice.
Authors
- Hongzhu Li (ORCID: https://orcid.org/0000-0002-1037-9101)
- Lian Liu (ORCID: https://orcid.org/0000-0002-1833-9841)
- Lanfeng Lai
- Bo Luo (ORCID: https://orcid.org/0000-0001-8519-4446)
- Xin Li (ORCID: https://orcid.org/0000-0003-0469-5121)
- Zhimin Li (ORCID: https://orcid.org/0000-0002-8284-1983)
- Yuying Zhang (ORCID: https://orcid.org/0000-0001-6888-2458)
- Yi Wei (ORCID: https://orcid.org/0000-0002-6335-6341)
- Jiaying Zhao (ORCID: https://orcid.org/0000-0002-6009-0568)
- Nenggui Xu (ORCID: https://orcid.org/0000-0002-8002-2204)
- Yang Han (ORCID: https://orcid.org/0000-0002-4802-2992)
Institutions
- Guangzhou University of Chinese Medicine (CN)
- Foshan Hospital of TCM (CN)
- Guangzhou Eighth People's Hospital (CN)
Publication Details
- Journal
- PubMed
- Published
- 2025-04-25
- DOI
- https://doi.org/10.13702/j.1000-0607.20240214
- Citations
- 1
- Primary Topic
- Medicinal Plants and Bioactive Compounds
- Type
- article