Diazoxide Choline (Vykat XR) for Prader-Willi Syndrome-Associated Hyperphagia

The FDA has approved diazoxide choline extended-release tablets (Vykat XR – Soleno Therapeutics) for treatment of hyperphagia in patients ≥4 years old with Prader-Willi syndrome. Diazoxide choline is the first drug to be approved in the US for this indication. Diazoxide oral suspension (Proglycem) has been available for years for management of symptomatic hypoglycemia.

Publication Details

Journal
˜The œmedical letter on drugs and therapeutics/˜The œmedical letter
Published
2025-04-28
DOI
https://doi.org/10.58347/tml.2025.1727e
Primary Topic
Genetic Syndromes and Imprinting
Type
article
Field-Weighted Citation Impact
0.00
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article

Diazoxide Choline (Vykat XR) for Prader-Willi Syndrome-Associated Hyperphagia

˜The œmedical letter on drugs and therapeutics/˜The œmedical letter
Genetic Syndromes and Imprinting
article

Diazoxide Choline (Vykat XR) for Prader-Willi Syndrome-Associated Hyperphagia

article en

Abstract

The FDA has approved diazoxide choline extended-release tablets (Vykat XR – Soleno Therapeutics) for treatment of hyperphagia in patients ≥4 years old with Prader-Willi syndrome. Diazoxide choline is the first drug to be approved in the US for this indication. Diazoxide oral suspension (Proglycem) has been available for years for management of symptomatic hypoglycemia.

˜The œmedical letter on drugs and therapeutics/˜The œmedical letterVol. 67(1727)
Openalex Percentile: Top 90%
Genetic Syndromes and Imprinting
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Diazoxide Choline (Vykat XR) for Prader-Willi Syndrome-Associated Hyperphagia · ˜The œmedical letter on drugs and therapeutics/˜The œmedical letter (2025) | TGRS Research Map | TGRS