In Brief: A New Indication for Tenecteplase (TNKase)

The tissue plasminogen activator (tPA) tenecteplase (TNKase – Genentech) has been approved by the FDA for treatment of acute ischemic stroke in adults. It is the second tPA to be approved in the US for this indication; alteplase (Activase) was approved in 1996. Tenecteplase was approved in 2000 to reduce the risk of death associated with acute ST-elevation myocardial infarction (STEMI).

Publication Details

Journal
˜The œmedical letter on drugs and therapeutics/˜The œmedical letter
Published
2025-04-28
DOI
https://doi.org/10.58347/tml.2025.1727d
Primary Topic
Machine Learning in Bioinformatics
Type
article
Field-Weighted Citation Impact
0.00
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article

In Brief: A New Indication for Tenecteplase (TNKase)

˜The œmedical letter on drugs and therapeutics/˜The œmedical letter
Machine Learning in Bioinformatics
article

In Brief: A New Indication for Tenecteplase (TNKase)

article en

Abstract

The tissue plasminogen activator (tPA) tenecteplase (TNKase – Genentech) has been approved by the FDA for treatment of acute ischemic stroke in adults. It is the second tPA to be approved in the US for this indication; alteplase (Activase) was approved in 1996. Tenecteplase was approved in 2000 to reduce the risk of death associated with acute ST-elevation myocardial infarction (STEMI).

˜The œmedical letter on drugs and therapeutics/˜The œmedical letterVol. 67(1727)
Openalex Percentile: Top 92%
Machine Learning in Bioinformatics
DOISourceOpenAlex
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In Brief: A New Indication for Tenecteplase (TNKase) · ˜The œmedical letter on drugs and therapeutics/˜The œmedical letter (2025) | TGRS Research Map | TGRS