Antibiotic treatment of <i>Stenotrophomonas maltophilia</i> bacteraemia: does trimethoprim/sulfamethoxazole dose affect clinical outcomes?

High-dose trimethoprim/sulfamethoxazole for S. maltophilia bacteraemia was not associated with improved outcomes while more frequent adverse drug events were observed. The sample size and retrospective design limit the study's conclusions. Future studies that address these limitations are needed to confirm the results.

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Publication Details

Journal
Journal of Antimicrobial Chemotherapy
Published
2025-04-24
DOI
https://doi.org/10.1093/jac/dkaf131
Citations
4
Primary Topic
Infections and bacterial resistance
Type
article
Field-Weighted Citation Impact
7.19

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article

Antibiotic treatment of Stenotrophomonas maltophilia bacteraemia: does trimethoprim/sulfamethoxazole dose affect clinical outcomes?

Chien-Liang Chen, Hung-Sheng Shang, L. Kristopher Siu, Weiping Chen et al.
4 citations
Journal of Antimicrobial Chemotherapy
Infections and bacterial resistance
7.19
article

Antibiotic treatment of Stenotrophomonas maltophilia bacteraemia: does trimethoprim/sulfamethoxazole dose affect clinical outcomes?

Chien-Liang Chen, Hung-Sheng Shang, L. Kristopher Siu, Weiping Chen, Ya-Sung Yang, Jung-Chung Lin, Ching-Mei Yu, Ching-Hsun Wang, Feng‐Yee Chang
article en
4 citations

Abstract

High-dose trimethoprim/sulfamethoxazole for S. maltophilia bacteraemia was not associated with improved outcomes while more frequent adverse drug events were observed. The sample size and retrospective design limit the study's conclusions. Future studies that address these limitations are needed to confirm the results.

Journal of Antimicrobial ChemotherapyVol. 80(6)
Tri-Service General Hospital (TW), National Health Research Institutes (TW), Zuoying Armed Forces General Hospital (TW), Taoyuan Armed Forces General Hospital (TW), National Defense Medical Center (TW)
Tri-Service General Hospital
Good health and well-being
Openalex Percentile: Top 3%
Infections and bacterial resistance
7.19
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