The real-world safety profile of pemetrexed and platinum with or without pembrolizumab: insights from a comparative analysis of FAERS database

In the real world, combination therapy increases the risk of certain AEs, particularly in specific patient subgroups. These findings emphasize the importance of personalized treatment strategies and AE monitoring, particularly during the first three months of therapy.

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Publication Details

Journal
BMC Cancer
Published
2025-04-24
DOI
https://doi.org/10.1186/s12885-025-14171-3
Citations
6
Primary Topic
Cancer Immunotherapy and Biomarkers
Type
article
Field-Weighted Citation Impact
6.27
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article

The real-world safety profile of pemetrexed and platinum with or without pembrolizumab: insights from a comparative analysis of FAERS database

Yanwen Zhou, Zhifei Huang, Shun Li, Hao Jiang et al.
6 citations
BMC Cancer
Cancer Immunotherapy and Biomarkers
6.27
article

The real-world safety profile of pemetrexed and platinum with or without pembrolizumab: insights from a comparative analysis of FAERS database

Yanwen Zhou, Zhifei Huang, Shun Li, Hao Jiang, Xiaoyu Zhong
article en
6 citations

Abstract

In the real world, combination therapy increases the risk of certain AEs, particularly in specific patient subgroups. These findings emphasize the importance of personalized treatment strategies and AE monitoring, particularly during the first three months of therapy.

BMC CancerVol. 25(1)
Bengbu Medical College (CN), First Affiliated Hospital of Bengbu Medical College (CN)
Openalex Percentile: Top 3%
Cancer Immunotherapy and Biomarkers
6.27
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