Polymyositis Presenting With Respiratory Failure and Cardiac Arrest: A Case Report

This case report presents a 30-year-old woman who experienced respiratory failure and cardiac arrest as a complication of polymyositis, which is an idiopathic inflammatory myopathy disease. Autoimmune diseases, such as polymyositis, can cause respiratory failure due to respiratory muscle weakness or interstitial lung involvement, leading to significant complications if not promptly addressed. The patient's complex clinical presentation included progressive muscle weakness, respiratory distress, and cardiac instability, underscoring the necessity for a comprehensive diagnostic approach. The report details the patient's clinical course, diagnostic workup, and multidisciplinary management, which involved immunosuppressive therapy, mechanical ventilation, and physiotherapy. This case emphasizes the critical role of a coordinated, multidisciplinary team in diagnosing and managing severe autoimmune diseases with multisystem involvement.

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Journal
Cureus
Published
2025-04-24
DOI
https://doi.org/10.7759/cureus.82887
Primary Topic
Inflammatory Myopathies and Dermatomyositis
Type
article
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article

Polymyositis Presenting With Respiratory Failure and Cardiac Arrest: A Case Report

Murad M Mawlawi, Ammar Z Faloudah, Mohannad AbuRageila, Ahmed Y Shebly et al.
Cureus
Inflammatory Myopathies and Dermatomyositis
article

Polymyositis Presenting With Respiratory Failure and Cardiac Arrest: A Case Report

Murad M Mawlawi, Ammar Z Faloudah, Mohannad AbuRageila, Ahmed Y Shebly, Jeehad M Felemban
article en

Abstract

This case report presents a 30-year-old woman who experienced respiratory failure and cardiac arrest as a complication of polymyositis, which is an idiopathic inflammatory myopathy disease. Autoimmune diseases, such as polymyositis, can cause respiratory failure due to respiratory muscle weakness or interstitial lung involvement, leading to significant complications if not promptly addressed. The patient's complex clinical presentation included progressive muscle weakness, respiratory distress, and cardiac instability, underscoring the necessity for a comprehensive diagnostic approach. The report details the patient's clinical course, diagnostic workup, and multidisciplinary management, which involved immunosuppressive therapy, mechanical ventilation, and physiotherapy. This case emphasizes the critical role of a coordinated, multidisciplinary team in diagnosing and managing severe autoimmune diseases with multisystem involvement.

CureusVol. 17(4)
Security Forces Hospital (SA), King Abdullah Medical City (SA)
Good health and well-being
Openalex Percentile: Top 88%
Inflammatory Myopathies and Dermatomyositis
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Polymyositis Presenting With Respiratory Failure and Cardiac Arrest: A Case Report — Murad M Mawlawi, Ammar Z Faloudah, et al. · Cureus (2025) | TGRS Research Map | TGRS