Mortality predictors and diagnostic challenges in adult tuberculous meningitis: a retrospective cohort of 100 patients

TBM remains a critical concern with significant mortality and morbidity. Key predictors of mortality, including altered consciousness, hydrocephalus, and older age, highlight the need for early detection and tailored interventions. In most cases, the diagnosis cannot be definitively confirmed and is instead categorized as probable or possible. Our study demonstrates that survival rates were comparable across definite, probable, and possible TBM categories, supporting the value of empirical treatment when definitive confirmation is not feasible.

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Publication Details

Journal
Tropical Medicine and Health
Published
2025-04-24
DOI
https://doi.org/10.1186/s41182-025-00738-0
Citations
6
Primary Topic
Infectious Diseases and Tuberculosis
Type
article
Field-Weighted Citation Impact
12.04
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article

Mortality predictors and diagnostic challenges in adult tuberculous meningitis: a retrospective cohort of 100 patients

Matin Shirazinia, Mahboubeh Haddad, Fereshte Sheybani, Maliheh Dadgarmoghaddam et al.
6 citations
Tropical Medicine and Health
Infectious Diseases and Tuberculosis
12.04
article

Mortality predictors and diagnostic challenges in adult tuberculous meningitis: a retrospective cohort of 100 patients

Matin Shirazinia, Mahboubeh Haddad, Fereshte Sheybani, Maliheh Dadgarmoghaddam, Mohammad Farhadi Rad
article en
6 citations

Abstract

TBM remains a critical concern with significant mortality and morbidity. Key predictors of mortality, including altered consciousness, hydrocephalus, and older age, highlight the need for early detection and tailored interventions. In most cases, the diagnosis cannot be definitively confirmed and is instead categorized as probable or possible. Our study demonstrates that survival rates were comparable across definite, probable, and possible TBM categories, supporting the value of empirical treatment when definitive confirmation is not feasible.

Tropical Medicine and HealthVol. 53(1)
Mashhad University of Medical Sciences (IR)
Good health and well-being
Openalex Percentile: Top 1%
Infectious Diseases and Tuberculosis
12.04
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