Crystal structure and Hirshfeld surface analysis of ketorolac tromethamine
Ketorolac tromethamine or 1,3-dihy-droxy-2-(hy-droxy-meth-yl)propan-2-am-inium 5-benzoyl-2,3-di-hydro-1<i>H</i>-pyrrolizine-1-carboxyl-ate, C<sub>15</sub>H<sub>12</sub>NO<sub>3</sub> <sup>+</sup>·C<sub>4</sub>H<sub>12</sub>NO<sub>3</sub> <sup>-</sup>, was studied by single-crystal and powder X-ray diffraction methods. One cation and one anion are present in the asymmetric unit. In the crystal, N-H⋯O and O-H⋯O hy-dro-gen bonds link the cation and anion. All the hy-dro-gen-bond inter-actions result in the formation of a di-periodic layer in the (100) crystallographic plane.
Authors
- Anna N. Puzan (ORCID: https://orcid.org/0000-0001-7766-4444)
- В.Н. Баумер (ORCID: https://orcid.org/0000-0003-4158-4981)
- Vitalii V. Rudiuk (ORCID: https://orcid.org/0000-0003-3440-1139)
Institutions
- State Scientific Institution “Institute for Single Crystals” of National Academy of Sciences of Ukraine (UA)
Publication Details
- Journal
- Acta Crystallographica Section E Crystallographic Communications
- Published
- 2025-04-24
- DOI
- https://doi.org/10.1107/s2056989025003226
- Primary Topic
- Synthesis and Catalytic Reactions
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Academy of Sciences of Ukraine