EVALUATING THE EFFECT OF VITAMIN D SUPPLEMENTATION ON PROTEINURIA IN PATIENTS WITH TYPE 2 DIABETES MELLITUS, FOCUSING ON CHANGES IN THE URINARY ALBUMIN/CREATATININE RATIO (UACR)

Introduction: Vitamin D deficiency exists to a high extent among patients with type 2 diabetes mellitus (T2DM) because it contributes to proteinuria development in diabetic nephropathy. The research examines vitamin D supplementation effects on T2DM patient proteinuria while focusing specifically on urinary albumin/creatinine ratio modifications (UACR). Objective: The analysis aims to determine the influence of vitamin D supplements on proteinuria coupled with HbA1c and UACR levels management for T2DM patients. Materials and Method: This randomized controlled trial was conducted at the Punjab Institute of Diabetes and Endocrinology in Lahore between January 2024 to June 2024. The research team randomly placed participants into groups that received either vitamin D supplements or inactive substances. The research design includes testing UACR levels and HbA1c levels before and after implementation. Results: Vitamin D supplements decreased UAR measurements by 30% while lowering HbA1c readings by 7.7% versus the placebo test recipients. Conclusion: The administration of vitamin D shows effectiveness in both lowering proteinuria and controlling blood glucose in patients with T2DM.