Cancer-derived exosomal circTMEM56 enhances the efficacy of HCC radiotherapy through the miR-136-5p/STING axis
High circTMEM56 expression in HCC modulates the distant effects of HCC RT by activating the cGAS-STING pathway to reshape the tumor microenvironment. This study provides a new approach to improve RT efficacy for HCC.
Authors
- Ai‐Wu Ke (ORCID: https://orcid.org/0000-0002-7964-6909)
- Yue Wang (ORCID: https://orcid.org/0000-0001-6636-354X)
- Junjie Cheng (ORCID: https://orcid.org/0000-0003-0502-6712)
- Shisuo Du (ORCID: https://orcid.org/0009-0007-5295-3064)
- Zhao‐Chong Zeng (ORCID: https://orcid.org/0000-0003-4330-3688)
- Yiming Zheng (ORCID: https://orcid.org/0000-0002-5739-5192)
- Kunchao Li
- Yuan Li (ORCID: https://orcid.org/0000-0001-9809-9894)
- S. Lin (ORCID: https://orcid.org/0000-0003-0312-0588)
- Aying Ma
- Chao Gao (ORCID: https://orcid.org/0000-0002-8381-7416)
Institutions
- Nanchang University (CN)
- Sun Yat-sen University (CN)
- Bengbu Medical College (CN)
- Fudan University (CN)
- Second Affiliated Hospital of Nanchang University (CN)
- Zhongshan Hospital (CN)
- The First Affiliated Hospital, Sun Yat-sen University (CN)
Publication Details
- Journal
- Cancer Biology and Medicine
- Published
- 2025-04-23
- DOI
- https://doi.org/10.20892/j.issn.2095-3941.2024.0544
- Citations
- 7
- Primary Topic
- Circular RNAs in diseases
- Type
- article
- Field-Weighted Citation Impact
- 5.64