A Rare Case of Concomitant Duodenal and Gallbladder Perforation in a Pediatric Patient

Concomitant perforation of the duodenum and gallbladder is exceptionally rare in the pediatric population. These conditions pose significant diagnostic and therapeutic challenges, particularly in critically ill or sedated children. We report the case of a five-year-old girl who was initially hospitalized for posterior fossa tumor resection and developed acute abdominal distension, anemia, and hematemesis in the postoperative period. Imaging was limited because of the hemodynamic instability. Emergency exploratory laparotomy revealed a large duodenal perforation and a concomitant gallbladder perforation. The surgical management included primary duodenal repair, cholecystectomy, and gastroduodenal bypass. Despite intensive supportive care, the patient succumbed to sepsis and multiorgan failure on postoperative day 2. This case highlights the diagnostic difficulty of gastrointestinal perforations in sedated intensive care unit patients, the possible pathophysiological link between duodenal ulcers and adjacent gallbladder inflammation, and the urgency for surgical intervention. Clinicians should maintain a high index of suspicion of stress-related gastrointestinal complications in critically ill children. Early surgical exploration may be life-saving when imaging is inconclusive and clinical deterioration is rapid.

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Journal
Cureus
Published
2025-04-23
DOI
https://doi.org/10.7759/cureus.82838
Primary Topic
Gallbladder and Bile Duct Disorders
Type
article
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article

A Rare Case of Concomitant Duodenal and Gallbladder Perforation in a Pediatric Patient

Hicham Zerhouni, Mohamed Lahlou, Basma Elkhannoussi, Mouna Khmou et al.
Cureus
Gallbladder and Bile Duct Disorders
article

A Rare Case of Concomitant Duodenal and Gallbladder Perforation in a Pediatric Patient

Hicham Zerhouni, Mohamed Lahlou, Basma Elkhannoussi, Mouna Khmou, Soufiane Essamoud, R. Bennani, Achraf Benmazhar, Yannis Ennachachibi
article en

Abstract

Concomitant perforation of the duodenum and gallbladder is exceptionally rare in the pediatric population. These conditions pose significant diagnostic and therapeutic challenges, particularly in critically ill or sedated children. We report the case of a five-year-old girl who was initially hospitalized for posterior fossa tumor resection and developed acute abdominal distension, anemia, and hematemesis in the postoperative period. Imaging was limited because of the hemodynamic instability. Emergency exploratory laparotomy revealed a large duodenal perforation and a concomitant gallbladder perforation. The surgical management included primary duodenal repair, cholecystectomy, and gastroduodenal bypass. Despite intensive supportive care, the patient succumbed to sepsis and multiorgan failure on postoperative day 2. This case highlights the diagnostic difficulty of gastrointestinal perforations in sedated intensive care unit patients, the possible pathophysiological link between duodenal ulcers and adjacent gallbladder inflammation, and the urgency for surgical intervention. Clinicians should maintain a high index of suspicion of stress-related gastrointestinal complications in critically ill children. Early surgical exploration may be life-saving when imaging is inconclusive and clinical deterioration is rapid.

CureusVol. 17(4)
Mohammed V University (MA), International Labour Organization (CH), Université Mohammed VI des Sciences et de la Santé (MA), Hôpital Universitaire International Cheikh Khalifa (MA), Institut National d'Oncologie (MA)
Zero hunger
Openalex Percentile: Top 87%
Gallbladder and Bile Duct Disorders
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