From genetic to postgenomic determinisms: The role of the environment reconsidered

In the past twenty years, conceptual and technological shifts in the life sciences have unseated the causal primacy of the gene. The picture emerging from 'postgenomic' science is one that emphasises multifactorial dependencies between the environment, development, and the genome, and blurs boundaries between biological individuals, and between the body and the environment. Despite the rejection of genetic determinism within postgenomics, forms of determinism nevertheless persist. The environment is often conceptualised in postgenomic research in a narrow and constrained way, affording an outsized causal role to certain environmental factors while neglecting the influence of others. This carries ethical and social implications, including for understandings of race and motherhood. This topical collection interrogates the environmental determinisms developing within postgenomic science, through investigation of their conceptual foundations, histories, and social contexts across a range of postgenomic fields.

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Publication Details

Journal
History & Philosophy of the Life Sciences
Published
2025-04-23
DOI
https://doi.org/10.1007/s40656-025-00672-8
Citations
2
Primary Topic
Race, Genetics, and Society
Type
article
Field-Weighted Citation Impact
3.63

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article

From genetic to postgenomic determinisms: The role of the environment reconsidered

Azita Chellappoo, Maurizio Meloni, Jan Baedke
2 citations
History & Philosophy of the Life Sciences
Race, Genetics, and Society
3.63
article

From genetic to postgenomic determinisms: The role of the environment reconsidered

Azita Chellappoo, Maurizio Meloni, Jan Baedke
article en
2 citations

Abstract

In the past twenty years, conceptual and technological shifts in the life sciences have unseated the causal primacy of the gene. The picture emerging from 'postgenomic' science is one that emphasises multifactorial dependencies between the environment, development, and the genome, and blurs boundaries between biological individuals, and between the body and the environment. Despite the rejection of genetic determinism within postgenomics, forms of determinism nevertheless persist. The environment is often conceptualised in postgenomic research in a narrow and constrained way, affording an outsized causal role to certain environmental factors while neglecting the influence of others. This carries ethical and social implications, including for understandings of race and motherhood. This topical collection interrogates the environmental determinisms developing within postgenomic science, through investigation of their conceptual foundations, histories, and social contexts across a range of postgenomic fields.

History & Philosophy of the Life SciencesVol. 47(2)
Deakin University (AU), The Open University (GB), Ruhr University Bochum (DE)
Deutsche Forschungsgemeinschaft
Responsible consumption and production, Life in Land
Openalex Percentile: Top 8%
Race, Genetics, and Society
3.63
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From genetic to postgenomic determinisms: The role of the environment reconsidered — Azita Chellappoo, Maurizio Meloni, et al. · History & Philosophy of the Life Sciences (2025) | TGRS Research Map | TGRS