Clinical characteristics of anti‐neurofascin 155 antibody‐positive autoimmune nodopathy in children

Pediatric anti-NF155 antibody autoimmune nodopathy was uncommon, featuring male dominance, and distal weakness with sensory symptoms. Additionally, the CSF protein levels were significantly elevated in seropositive patients. As IVIG treatment was ineffective, early immunosuppressive therapy was recommended. Early diagnosis and treatment are critical in reducing myelin and axonal damage.

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Publication Details

Journal
Pediatric Investigation
Published
2025-04-23
DOI
https://doi.org/10.1002/ped4.70008
Citations
3
Primary Topic
Peripheral Neuropathies and Disorders
Type
article
Field-Weighted Citation Impact
4.17

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article

Clinical characteristics of anti‐neurofascin 155 antibody‐positive autoimmune nodopathy in children

Jiuwei Li, Hui Xiong, Yun Peng, Junlan Lu et al.
3 citations
Pediatric Investigation
Peripheral Neuropathies and Disorders
4.17
article

Clinical characteristics of anti‐neurofascin 155 antibody‐positive autoimmune nodopathy in children

Jiuwei Li, Hui Xiong, Yun Peng, Junlan Lu, Xiaona Fu, Ge Lin, Siwei Wang, Yongxiang Zhao, Xinying Yang, Shuai Gong, Weihua Zhang, Shen Zhang, Liyuan Cui, Bingbing Jia
article en
3 citations

Abstract

Pediatric anti-NF155 antibody autoimmune nodopathy was uncommon, featuring male dominance, and distal weakness with sensory symptoms. Additionally, the CSF protein levels were significantly elevated in seropositive patients. As IVIG treatment was ineffective, early immunosuppressive therapy was recommended. Early diagnosis and treatment are critical in reducing myelin and axonal damage.

Pediatric InvestigationVol. 9(3)
Capital Medical University (CN), Beijing Children’s Hospital (CN)
National Natural Science Foundation of China
Openalex Percentile: Top 7%
Peripheral Neuropathies and Disorders
4.17
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