Venetoclax Alone or in Combination With Chemotherapy in Paediatric and Adolescent/Young Adult Patients With Relapsed/Refractory Acute Myeloid Leukaemia
Venetoclax alone or combined with chemotherapy was well tolerated in paediatric and adolescent/young adult patients with relapsed/refractory AML, with promising, although transient, responses with venetoclax plus HDAC or azacitidine.
Authors
- Seth E. Karol (ORCID: https://orcid.org/0000-0001-8113-8180)
- Gauri Sunkersett
- André Baruchel (ORCID: https://orcid.org/0000-0003-0120-6089)
- Christian Flotho (ORCID: https://orcid.org/0000-0001-9367-0553)
- Christopher J. Forlenza (ORCID: https://orcid.org/0000-0003-2246-1206)
- C. Michel Zwaan (ORCID: https://orcid.org/0000-0001-6892-8268)
- Fengjiao Dunbar
- Seong Lin Khaw (ORCID: https://orcid.org/0000-0002-9084-8974)
- Daniel A. Morgenstern (ORCID: https://orcid.org/0000-0002-4859-1108)
- Diana Dunshee (ORCID: https://orcid.org/0000-0001-8930-1587)
- Andrew E. Place (ORCID: https://orcid.org/0000-0002-9604-4213)
- Todd M. Cooper (ORCID: https://orcid.org/0000-0002-1203-2371)
- Arnaud Petit (ORCID: https://orcid.org/0000-0001-8363-1622)
- Christopher Fraser
- Tammy L. Palenski (ORCID: https://orcid.org/0000-0003-0675-7728)
- David S. Ziegler (ORCID: https://orcid.org/0000-0001-7451-7916)
- Joseph T. Opferman (ORCID: https://orcid.org/0000-0002-1147-5621)
- Ahmed Hamed Salem (ORCID: https://orcid.org/0000-0002-9261-1583)
- Jeremy A. Ross (ORCID: https://orcid.org/0000-0002-8458-7819)
- Margaret E. Macy (ORCID: https://orcid.org/0000-0001-6446-9180)
- Jeffrey E. Rubnitz (ORCID: https://orcid.org/0000-0001-9885-3527)
- Maureen M. O’Brien (ORCID: https://orcid.org/0000-0002-9054-4321)
- Maika Onishi
- Deeksha Vishwamitra
- Dirk Reinhardt (ORCID: https://orcid.org/0000-0002-7027-4483)
- Henrique Bittencourt (ORCID: https://orcid.org/0000-0002-5507-8310)
- Xin Chen (ORCID: https://orcid.org/0000-0001-6261-0291)
- Kelly C. Goldsmith (ORCID: https://orcid.org/0000-0001-8672-2298)
- Kristina Unnebrink
- Maja Kammerlander
Institutions
- Ain Shams University (EG)
- Cincinnati Children's Hospital Medical Center (US)
- Seattle Children's Hospital (US)
- St. Jude Children's Research Hospital (US)
- Royal Children's Hospital (AU)
- Memorial Sloan Kettering Cancer Center (US)
- Emory University (US)
- University of Freiburg (DE)
- University of Toronto (CA)
- Université Paris Cité (FR)
- University Medical Center Freiburg (DE)
- Hospital for Sick Children (CA)
- Centre Hospitalier Universitaire Sainte-Justine (CA)
- AbbVie (United States) (US)
- UNSW Sydney (AU)
- Sorbonne Université (FR)
- Hôpital Armand-Trousseau (FR)
- Children's Hospital Colorado (US)
- Assistance Publique – Hôpitaux de Paris (FR)
- Center for Cancer and Blood Disorders (US)
- Sydney Children's Hospital (AU)
- Hôpital Robert-Debré (FR)
- Princess Máxima Center (NL)
- AbbVie (Germany) (DE)
- SickKids Foundation (CA)
- Erasmus MC - Sophia Children’s Hospital (NL)
- Children's Healthcare of Atlanta (US)
- Dana-Farber/Boston Children's Cancer and Blood Disorders Center (US)
- Children's Health Queensland Hospital and Health Service (AU)
- University of Duisburg-Essen (DE)
- University of Cincinnati (US)
- University of Colorado Denver (US)
Publication Details
- Journal
- Pediatric Blood & Cancer
- Published
- 2025-04-23
- DOI
- https://doi.org/10.1002/pbc.31714
- Citations
- 2
- Primary Topic
- Acute Myeloid Leukemia Research
- Type
- article
- Field-Weighted Citation Impact
- 3.54
Funders
- Genentech