Formulation, Characterisation and In Vitro Evaluation of Herbosome Sunscreen Lotion

Introduction: The global market for sunscreen ingredients is rising day by day. Herbosomes are essentially the substance encapsulated in liposomes, which are tiny vesicles with a lipid bilayer. The benefits lie in the enhanced bioavailability and targeted delivery of the active ingredients. Material and Methods: Herbosomes were prepared by using aloe vera and resveratrol in various ratios against phosphotidylcholine. Herbosomes of aloe vera and resveratrol were incorporated into the lotion. Two formulations, F1 and F2, of herbosome lotion were prepared. Results and Discussion: This study set out to develop and standardize herbosomal sunscreen lotion that has a significant sun protection factor and enticing qualities. The sunscreen lotions F1 and F2 were developed using two distinct ratios of aloe and resveratrol, and their physicochemical properties and SPF were also assessed. Herbosme lotion thus formed was evaluated for visualization, homogeneity, viscosity, irritancy test, spreadability, and pH. The efficacy of the developed formulation, which possesses SPF in the range of 19 to 23, when tested with a standard, was observed to be satisfactory to that of a marketed sunscreen with SPF 55. Conclusion: In this research study, formulation F2 was found to have a higher SPF and be more stable and effective than formulation F1