Sex hormones correlate with heart rate variability in healthy women and this correlation is conserved in women with well-controlled type 2 diabetes mellitus
All sex hormones correlate with HRV indices. Regression analysis confirms that this correlation is independent from the mean heartbeat interval. However, in regression models adjusted for age and glucose levels, only estradiol was found to be significant, and should be considered an important variable related to cardiovascular and autonomic balance in T2DM women and may provide crucial information to improve cardiovascular risk algorithms.
Authors
- Adriana Robles-Cabrera (ORCID: https://orcid.org/0000-0001-7207-9991)
- Claudia Lerma (ORCID: https://orcid.org/0000-0002-4679-7751)
- Silvia Ruiz‐Velasco (ORCID: https://orcid.org/0000-0002-9220-2368)
- Rubén Fossión (ORCID: https://orcid.org/0000-0001-8456-2075)
- Iván Pérez-Díaz (ORCID: https://orcid.org/0000-0002-0945-301X)
Institutions
- Universidad Autónoma de la Ciudad de México (MX)
- Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán (MX)
- Instituto Nacional de Cardiología (MX)
- Universidad Nacional Autónoma de México (MX)
- Tecnológico de Monterrey (MX)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-04-23
- DOI
- https://doi.org/10.1371/journal.pone.0320982
- Citations
- 1
- Primary Topic
- Heart Rate Variability and Autonomic Control
- Type
- article
- Field-Weighted Citation Impact
- 1.39
Funders
- Dirección General de Asuntos del Personal Académico, Universidad Nacional Autónoma de México