The Effect of Kokilaksha Ghanavati & Guduchi Ghanavati in the management of Vatarakta (Gout) – A Randomised Clinical Study

Background: Amid the joint conditions outlined in the texts of Ayurveda, Vatarakta (Gout) is the most common type of inflammatory arthritis; its rising global prevalence is the outcome of rapid modernization and faulty dietary practices, and has a significant detrimental effect on health, quality of life and productivity. Objective: To compare the efficacy of Kokilaksha Ghanavati and Guduchi Ghanavati in Vatarakta (gout). Materials and Methods: The present trial was a randomised clinical study. Computer-generated randomization and participants fufilling the criteria of vatarakta symptoms were recruited in two groups. Group A intervened with Kokilaksha Ghanavati and Group B with Guduchi Ghanavati for 14 days, with follow-up on 7th day and assessed with subjective and objective parameters. Results: The findings of the research revealed that Group B had statistically significant improvement compared to Group A on the Sandhi shoola (joint pain), sankochan (stiffness), visual analog scale (VAS) score, while Group A considerably outperformed Group B with regard to improvement in Sandhi Shotha (joint swelling). Daha (burning sensation), sparsha-asahatva (tenderness) and serum uric acid showed comparable improvements in both the groups. Conclusion: Guduchi Ghanavati proved to outscore Kokilaksha Ghanavati in the management of Vatarakta. However, Kokilaksha Ghanavati showed major improvement in key feature of the disease (shotha-86.21%), along with visible improvement in other parameters as well. The positive impact of it on vatarakta is also undeniable.