Small Extracellular Vesicle (sEV) Uptake from Lung Adenocarcinoma and Squamous Cell Carcinoma Alters T-Cell Cytokine Expression and Modulates Protein Profiles in sEV Biogenesis
Lung cancer-derived sEVs regulate T-cell activities through immunoregulatory signaling. The molecular interactions between sEVs and immune cells can reveal novel tumor immune regulatory mechanisms and therapeutic targets.
Authors
- Alex George (ORCID: https://orcid.org/0000-0002-4962-3917)
- Hafiza Padinharayil (ORCID: https://orcid.org/0000-0001-8516-1943)
- Cornelia M. Wilson (ORCID: https://orcid.org/0000-0001-6584-6179)
- Jinsu Varghese (ORCID: https://orcid.org/0000-0002-9287-0374)
- Pulikkottil Raphael Varghese
Institutions
- Canterbury Christ Church University (GB)
- Jubilee Mission Medical College and Research Institute (IN)
Publication Details
- Journal
- Proteomes
- Published
- 2025-04-23
- DOI
- https://doi.org/10.3390/proteomes13020015
- Citations
- 1
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 0.81
Funders
- Canterbury Christ Church University
- Department of Biotechnology, Ministry of Science and Technology, India
- Indian Council of Medical Research
- Council of Scientific and Industrial Research, India
- VIT University