Structure-Function Associations Between Quantitative Contrast Sensitivity Function And Peripapillary Optical Coherence Tomography Angiography in Diabetic Retinopathy
Radial peripapillary capillary perfusion density worsens with onset of diabetes and increasing severity of DR while capillary flux index is more significantly affected later in disease. Structure-function associations suggest that DR-induced peripapillary microvascular changes are more strongly associated with contrast sensitivity changes than with visual acuity.
Authors
- Cade Bennett (ORCID: https://orcid.org/0009-0001-8195-2622)
- Grace Baldwin
- Itika Garg (ORCID: https://orcid.org/0000-0002-9537-8561)
- Sierra K. Ha
- Leo A. Kim (ORCID: https://orcid.org/0000-0001-9106-6416)
- Matthew J. Finn
- Peyman Razavi (ORCID: https://orcid.org/0000-0002-2650-152X)
- Isabella Stettler
- Ioanna Ploumi (ORCID: https://orcid.org/0000-0001-8475-3170)
- Demetrios G. Vavvas (ORCID: https://orcid.org/0000-0002-8622-6478)
- Filippos Vingopoulos (ORCID: https://orcid.org/0000-0003-3778-5473)
- Deeba Husain (ORCID: https://orcid.org/0000-0002-8494-0950)
- Francesco Romano (ORCID: https://orcid.org/0000-0002-0458-9727)
- Xinyi Ding (ORCID: https://orcid.org/0000-0001-9539-8178)
- Katherine M. Overbey (ORCID: https://orcid.org/0009-0001-1654-9159)
- Nimesh A. Patel
- John B. Miller
Institutions
- Massachusetts Eye and Ear Infirmary (US)
- Harvard University (US)
Publication Details
- Journal
- Investigative Ophthalmology & Visual Science
- Published
- 2025-04-23
- DOI
- https://doi.org/10.1167/iovs.66.4.69
- Citations
- 4
- Primary Topic
- Retinal Diseases and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 6.83
Funders
- Research to Prevent Blindness
- Sunovion
- Alimera Sciences
- Genentech
- Allergan
- Alcon Research Institute