Human platelet lysate produced from leukoreduction filter contents enables sufficient MSC growth
f-hPL derived from leukoreduction filters demonstrated strong capacity for MSCs expansion. The use of discarded blood materials for regenerative medicine represents a sustainable and efficient approach, with significant therapeutic potential.
Authors
- Miki Fujimura (ORCID: https://orcid.org/0000-0002-0991-0516)
- Shiho Kato
- Hisae Fuse
- Shuichi Kino
- Shinobu Wakamoto
- Sumio Ohtsuki (ORCID: https://orcid.org/0000-0003-4634-7133)
- Masahito Kawabori (ORCID: https://orcid.org/0000-0002-3574-8380)
- Yoshihiro Torimoto
- Tomoko Furukawa
- Mitsuaki Akino
Institutions
- Yahoo (United Kingdom) (GB)
- Hokkaido University (JP)
- Japanese Red Cross Society, Japan (JP)
- Rainbow Medical (Israel) (IL)
- Kumamoto University (JP)
Publication Details
- Journal
- Stem Cell Research & Therapy
- Published
- 2025-04-23
- DOI
- https://doi.org/10.1186/s13287-025-04329-y
- Citations
- 4
- Primary Topic
- Mesenchymal stem cell research
- Type
- article
- Field-Weighted Citation Impact
- 6.50
Funders
- Japan Agency for Medical Research and Development
- Japan Society for the Promotion of Science