Long-Lasting Cigarette Smoking Alterations in Immune Function Occur in Cannabis Smokers, Possibly Rendering Them Vulnerable to Smoking-Related Tumors in Later Life

We can confirm a previous report of epigenetic changes induced by cigarette smoking that may contribute to long-lasting alterations in immune function related to CXCL5 and CEACAM6. In addition, we have found that these same long-lasting smoking alterations in immune function related to CXCL5 and CEACAM6 occur in cannabis smokers, possibly rendering them vulnerable to smoking-related tumors in later life.

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Publication Details

Journal
American Journal of Clinical Oncology
Published
2025-04-23
DOI
https://doi.org/10.1097/coc.0000000000001203
Primary Topic
Cancer, Stress, Anesthesia, and Immune Response
Type
article
Field-Weighted Citation Impact
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article

Long-Lasting Cigarette Smoking Alterations in Immune Function Occur in Cannabis Smokers, Possibly Rendering Them Vulnerable to Smoking-Related Tumors in Later Life

Peter H. Rheinstein, Steven P. Lehrer
American Journal of Clinical Oncology
Cancer, Stress, Anesthesia, and Immune Response
article

Long-Lasting Cigarette Smoking Alterations in Immune Function Occur in Cannabis Smokers, Possibly Rendering Them Vulnerable to Smoking-Related Tumors in Later Life

Peter H. Rheinstein, Steven P. Lehrer
article en

Abstract

We can confirm a previous report of epigenetic changes induced by cigarette smoking that may contribute to long-lasting alterations in immune function related to CXCL5 and CEACAM6. In addition, we have found that these same long-lasting smoking alterations in immune function related to CXCL5 and CEACAM6 occur in cannabis smokers, possibly rendering them vulnerable to smoking-related tumors in later life.

American Journal of Clinical OncologyVol. 48(9)
Icahn School of Medicine at Mount Sinai (US)
Good health and well-being
Openalex Percentile: Top 89%
Cancer, Stress, Anesthesia, and Immune Response
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