Navigating the complexity of atypical teratoid/rhabdoid tumor (ATRT) in pediatric neuro-oncology: Insights from clinical spectrum to therapeutic challenges
This case underscores the complexities of ATRT management, emphasizing the importance of early diagnosis, aggressive multimodal therapy, and vigilant radiological follow-up. While ATRT shares imaging similarities with medulloblastomas, its distinct histopathological features necessitate tailored treatment strategies. Maximal safe resection, followed by intensive chemotherapy, remains the cornerstone of treatment, highlighting the need for a multidisciplinary approach to improve long-term outcomes in pediatric ATRT patients.
Authors
- Youssef G. Comair
- Ali Msheik (ORCID: https://orcid.org/0000-0002-4033-1985)
- Mohamad Yazbeck
- Abdulla Illeyan
Institutions
- Johns Hopkins Hospital (US)
- Hôpital Georges-Clemenceau (FR)
- Hamad Medical Corporation (QA)
Publication Details
- Journal
- International Journal of Surgery Case Reports
- Published
- 2025-04-23
- DOI
- https://doi.org/10.1016/j.ijscr.2025.111354
- Primary Topic
- Chromatin Remodeling and Cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.00