Navigating the complexity of atypical teratoid/rhabdoid tumor (ATRT) in pediatric neuro-oncology: Insights from clinical spectrum to therapeutic challenges

This case underscores the complexities of ATRT management, emphasizing the importance of early diagnosis, aggressive multimodal therapy, and vigilant radiological follow-up. While ATRT shares imaging similarities with medulloblastomas, its distinct histopathological features necessitate tailored treatment strategies. Maximal safe resection, followed by intensive chemotherapy, remains the cornerstone of treatment, highlighting the need for a multidisciplinary approach to improve long-term outcomes in pediatric ATRT patients.

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Publication Details

Journal
International Journal of Surgery Case Reports
Published
2025-04-23
DOI
https://doi.org/10.1016/j.ijscr.2025.111354
Primary Topic
Chromatin Remodeling and Cancer
Type
article
Field-Weighted Citation Impact
0.00
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article

Navigating the complexity of atypical teratoid/rhabdoid tumor (ATRT) in pediatric neuro-oncology: Insights from clinical spectrum to therapeutic challenges

Youssef G. Comair, Ali Msheik, Mohamad Yazbeck, Abdulla Illeyan
International Journal of Surgery Case Reports
Chromatin Remodeling and Cancer
article

Navigating the complexity of atypical teratoid/rhabdoid tumor (ATRT) in pediatric neuro-oncology: Insights from clinical spectrum to therapeutic challenges

Youssef G. Comair, Ali Msheik, Mohamad Yazbeck, Abdulla Illeyan
article en

Abstract

This case underscores the complexities of ATRT management, emphasizing the importance of early diagnosis, aggressive multimodal therapy, and vigilant radiological follow-up. While ATRT shares imaging similarities with medulloblastomas, its distinct histopathological features necessitate tailored treatment strategies. Maximal safe resection, followed by intensive chemotherapy, remains the cornerstone of treatment, highlighting the need for a multidisciplinary approach to improve long-term outcomes in pediatric ATRT patients.

International Journal of Surgery Case ReportsVol. 131(C)
Johns Hopkins Hospital (US), Hôpital Georges-Clemenceau (FR), Hamad Medical Corporation (QA)
Openalex Percentile: Top 92%
Chromatin Remodeling and Cancer
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