Serum C-C motif chemokine ligand 17 as a predictive biomarker for the progression of non-idiopathic pulmonary fibrosis interstitial lung disease
We identified serum CCL17 as a clinically measurable biomarker for predicting non-IPF-ILD progression. Serum CCL17 could enable the stratification of patients at risk of non-IPF-ILD progression, leading to appropriate early therapeutic intervention.
Authors
- Yoshikazu Inoue (ORCID: https://orcid.org/0000-0003-3994-874X)
- Yuko Abe (ORCID: https://orcid.org/0000-0003-3438-4201)
- Mari Tone (ORCID: https://orcid.org/0000-0002-8230-0757)
- Atsushi Kumanogoh (ORCID: https://orcid.org/0000-0003-4749-7117)
- Yujiro Naito
- Takayuki Niitsu (ORCID: https://orcid.org/0000-0003-4280-3074)
- Shohei Koyama (ORCID: https://orcid.org/0000-0002-6897-9417)
- Takehiro Hasegawa (ORCID: https://orcid.org/0000-0002-4635-4942)
- Kentaro Masuhiro (ORCID: https://orcid.org/0000-0002-8785-1726)
- Kota Iwahori (ORCID: https://orcid.org/0000-0002-9891-6003)
- Izumi Nagatomo (ORCID: https://orcid.org/0000-0001-5382-4327)
- Shigeyuki Shichino (ORCID: https://orcid.org/0000-0002-1683-2448)
- Kiyoharu Fukushima (ORCID: https://orcid.org/0000-0002-9767-7899)
- Satoshi Nojima (ORCID: https://orcid.org/0000-0002-5124-0026)
- Moritz Pohl (ORCID: https://orcid.org/0000-0002-2801-950X)
- Yuichi Adachi (ORCID: https://orcid.org/0000-0002-8867-3191)
- Ryuya Edahiro (ORCID: https://orcid.org/0000-0001-5009-6408)
- Hanako Yoshimura (ORCID: https://orcid.org/0000-0002-3717-3963)
- Takatoshi Enomoto (ORCID: https://orcid.org/0000-0002-1771-6684)
- Yoshito Takeda (ORCID: https://orcid.org/0000-0003-2905-6537)
- Reina Hara (ORCID: https://orcid.org/0000-0001-7013-4328)
- Satoshi Tanizaki
- Daisuke Nakatsubo (ORCID: https://orcid.org/0009-0004-0517-0874)
- Saori Amiya
- Yoshimi Noda
- Mana Nakayama
- Maiko Naito (ORCID: https://orcid.org/0000-0002-4360-7043)
- Kotaro Miyake (ORCID: https://orcid.org/0000-0002-6441-1699)
- Masahiro Yanagawa (ORCID: https://orcid.org/0000-0002-0911-6769)
- Makoto Yamamoto (ORCID: https://orcid.org/0000-0001-7844-331X)
- Hanna B. Lunding
- Yuya Shirai (ORCID: https://orcid.org/0000-0002-0518-9020)
- Haruhiko Hirata (ORCID: https://orcid.org/0000-0002-1134-7283)
- Takayuki Shiroyama (ORCID: https://orcid.org/0000-0002-2816-9428)
- Feng Zhao (ORCID: https://orcid.org/0000-0002-6612-1150)
- Takahiro Kawasaki (ORCID: https://orcid.org/0000-0002-8625-7899)
Institutions
- Tokyo University of Science (JP)
- Sysmex (Germany) (DE)
- RIKEN Center for Integrative Medical Sciences (JP)
- Fukujuji Hospital (JP)
- NHO Kinki Chuo Chest Medical Center (JP)
- Osaka International University (JP)
- Sysmex (Japan) (JP)
- The University of Osaka (JP)
Publication Details
- Journal
- Respiratory Research
- Published
- 2025-04-23
- DOI
- https://doi.org/10.1186/s12931-025-03237-2
- Citations
- 1
- Primary Topic
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Type
- article
- Field-Weighted Citation Impact
- 1.52
Funders
- Japan Agency for Medical Research and Development
- Japan Society for the Promotion of Science