Evidence to shared genetic correlation of ischemic stroke and intracerebral hemorrhage and cardiovascular related traits
Our study revealed the local genetic correlations between two stroke subtypes and ten common CRTs. Gene-level analyses indicated that biological explanations underlying these identified local genetic correlations may existed elsewhere beyond a common pattern of genetic-gene expression regulation.
Authors
- Peng Huang (ORCID: https://orcid.org/0000-0002-0146-921X)
- Wei He
- Haochang Li
- Yiming Qian (ORCID: https://orcid.org/0000-0002-1795-2038)
- Qin Shi (ORCID: https://orcid.org/0000-0002-9403-752X)
- Jiajia Shi (ORCID: https://orcid.org/0009-0000-3395-6859)
- Tao Fan (ORCID: https://orcid.org/0000-0001-8885-1480)
- Xuehong Cai
Institutions
- Jiangsu University (CN)
- Nanjing University of Chinese Medicine (CN)
- Shanghai University of Traditional Chinese Medicine (CN)
- Jiangyin People's Hospital (CN)
- First People's Hospital of Kunshan (CN)
- Traditional Chinese Medicine Hospital of Kunshan (CN)
- Southeast University (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-04-23
- DOI
- https://doi.org/10.1371/journal.pone.0320479
- Primary Topic
- Genetic Associations and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 0.00