Culture-Negative Subacute Lactobacillus Endocarditis Diagnosed by Microbial Cell-Free DNA Sequencing
This case underscores the importance of considering probiotics as a potential source of bacteremia in patients with negative cultures after surgery and highlights how metagenomic sequencing can identify pathogens and guide effective therapy in challenging cases.
Authors
- Stefan Lebrun
- Joseph D. Fontes (ORCID: https://orcid.org/0000-0003-4796-343X)
- Abduljabar Adi (ORCID: https://orcid.org/0000-0002-6147-6518)
- Maiko Kondo (ORCID: https://orcid.org/0000-0002-4130-9632)
- Miguel Alvarez Villela
Institutions
- Lenox Hill Hospital (US)
Publication Details
- Journal
- JACC Case Reports
- Published
- 2025-04-23
- DOI
- https://doi.org/10.1016/j.jaccas.2025.103505
- Citations
- 1
- Primary Topic
- Infective Endocarditis Diagnosis and Management
- Type
- article
- Field-Weighted Citation Impact
- 1.35