Association Between Metabolic Syndrome and Young-Onset Dementia
In this large Korean cohort, MetS and its individual components were significantly associated with an increased risk of YOD. These findings suggest that interventions targeting MetS may help mitigate YOD risk. However, the observational design precludes definitive causal inferences, and reliance on claims data could introduce misclassification bias. Future research using longitudinal designs and comprehensive data collection is needed to validate and expand on these associations.
Authors
- Jae‐Sung Lim (ORCID: https://orcid.org/0000-0001-6157-2908)
- Kyungdo Han (ORCID: https://orcid.org/0000-0002-6096-1263)
- Dae Young Cheon (ORCID: https://orcid.org/0000-0001-6713-4300)
- Minwoo Lee (ORCID: https://orcid.org/0000-0001-8474-5744)
- Jeong‐Yoon Lee (ORCID: https://orcid.org/0000-0002-4297-1791)
- Jonguk Kim (ORCID: https://orcid.org/0000-0002-3026-9532)
Institutions
- Soongsil University (KR)
- Soonchunhyang University Hospital Seoul (KR)
- Asan Medical Center (KR)
- Hallym University Dongtan Sacred Heart Hospital (KR)
- Inha University Hospital (KR)
- Hallym University Sacred Heart Hospital (KR)
Publication Details
- Journal
- Neurology
- Published
- 2025-04-23
- DOI
- https://doi.org/10.1212/wnl.0000000000213599
- Citations
- 5
- Primary Topic
- Diet and metabolism studies
- Type
- article
- Field-Weighted Citation Impact
- 5.82