The genetic landscape of sporadic adult-onset degenerative ataxia: a multi-modal genetic study of 377 consecutive patients from the longitudinal multi-centre SPORTAX cohort
This work was supported by the Clinician Scientist programme "PRECISE.net" funded by the Else Kröner-Fresenius-Stiftung (to DM, AT, CW, OR, and MS), by the Deutsche Forschungsgemeinschaft (as part of the PROSPAX project), and by the Canadian Institutes of Health Research and the Fondation Groupe Monaco. Support was also provided by Humboldt Research Fellowship for Postdocs and the Hertie-Network of Excellence in Clinical Neuroscience and a Fellowship award from the Canadian Institutes of Health Research.
Authors
- Tobias B. Haack (ORCID: https://orcid.org/0000-0001-6033-4836)
- Bart P.C. van de Warrenburg (ORCID: https://orcid.org/0000-0003-4412-1616)
- Thomas Klopstock (ORCID: https://orcid.org/0000-0003-2805-4652)
- Stefan Vielhaber (ORCID: https://orcid.org/0000-0002-4011-1106)
- Stephan Züchner (ORCID: https://orcid.org/0000-0002-8498-5235)
- David Pellerin (ORCID: https://orcid.org/0000-0002-5807-995X)
- David Mengel (ORCID: https://orcid.org/0000-0002-4133-7182)
- Florian Harmuth
- Zofia Fleszar
- Demet Önder
- Sylvia Boesch (ORCID: https://orcid.org/0000-0003-1657-7368)
- Jennifer Faber (ORCID: https://orcid.org/0000-0003-3265-0262)
- Dagmar Timmann (ORCID: https://orcid.org/0000-0003-1935-416X)
- Claudia Dufke (ORCID: https://orcid.org/0000-0001-5225-2443)
- Iselin Marie Wedding
- Gabriella Silvestri (ORCID: https://orcid.org/0000-0002-1950-1468)
- Andreas Traschütz (ORCID: https://orcid.org/0000-0002-8165-5898)
- Danique Beijer (ORCID: https://orcid.org/0000-0001-6593-7644)
- Carlo Wilke (ORCID: https://orcid.org/0000-0002-7250-8597)
- Ludger J. Schöls (ORCID: https://orcid.org/0000-0001-7774-5025)
- Christoph Kamm (ORCID: https://orcid.org/0000-0002-7618-2336)
- Bernard Brais
- Olaf Rieß
Institutions
- Università Cattolica del Sacro Cuore (IT)
- Oslo University Hospital (NO)
- Montreal Neurological Institute and Hospital (CA)
- Innsbruck Medical University (AT)
- Radboud University Nijmegen (NL)
- Universität Innsbruck (AT)
- University Hospital Bonn (DE)
- German Center for Neurodegenerative Diseases (DE)
- Agostino Gemelli University Polyclinic (IT)
- Radboud University Medical Center (NL)
- Klinikum Magdeburg (DE)
- Munich Cluster for Systems Neurology (DE)
- Essen University Hospital (DE)
- Dr. John T. Macdonald Foundation (US)
- Hertie Institute for Clinical Brain Research (DE)
- University of Rostock (DE)
- University of Duisburg-Essen (DE)
- University of Tübingen (DE)
- Ludwig-Maximilians-Universität München (DE)
Publication Details
- Journal
- EBioMedicine
- Published
- 2025-04-23
- DOI
- https://doi.org/10.1016/j.ebiom.2025.105715
- Citations
- 7
- Primary Topic
- Genetic Neurodegenerative Diseases
- Type
- article
- Field-Weighted Citation Impact
- 6.36
Funders
- Alexander von Humboldt-Stiftung
- Baden-Württemberg Stiftung
- Deutsche Forschungsgemeinschaft
- Else Kröner-Fresenius-Stiftung
- Gemeinnützige Hertie-Stiftung
- Canadian Institutes of Health Research
- Medizinischen Fakultät, Eberhard Karls Universität Tübingen