Effects of Sacubitril/Valsartan on Myocardial Tissue in Heart Failure With Left Ventricular Ejection Fraction Below 50%

ARNI reduced LV volume and mass, resulting from decreases in both extra- and intracellular mass, without changing ECV. This suggests ARNI has potential to improve LV tissue characteristics in HF patients with LVEF <50%.

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Institutions

Publication Details

Journal
Circulation Journal
Published
2025-04-23
DOI
https://doi.org/10.1253/circj.cj-24-0934
Citations
4
Primary Topic
Heart Failure Treatment and Management
Type
article
Field-Weighted Citation Impact
5.55
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article

Effects of Sacubitril/Valsartan on Myocardial Tissue in Heart Failure With Left Ventricular Ejection Fraction Below 50%

Masaki Ishiyama, Tairo Kurita, Kaoru Dohi, Taku Omori et al.
4 citations
Circulation Journal
Heart Failure Treatment and Management
5.55
article

Effects of Sacubitril/Valsartan on Myocardial Tissue in Heart Failure With Left Ventricular Ejection Fraction Below 50%

Masaki Ishiyama, Tairo Kurita, Kaoru Dohi, Taku Omori, Masaki Ishida, Itaru Goto, Takanori Kokawa, Takafumi Koji, Emiyo Sugiura, Hajime Sakuma, Shiro Nakamori, Naoki Fujimoto, Keishi Moriwaki, Yuichi Sato, Takashi Tanigawa, Hana Mizutani, Shuichi Murashima, Ryuji Okamoto
article en
4 citations

Abstract

ARNI reduced LV volume and mass, resulting from decreases in both extra- and intracellular mass, without changing ECV. This suggests ARNI has potential to improve LV tissue characteristics in HF patients with LVEF <50%.

Circulation JournalVol. 89(7)
Mie University (JP), Mie University Hospital (JP)
Good health and well-being
Openalex Percentile: Top 4%
Heart Failure Treatment and Management
5.55
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