Enhanced Electrochemical Dopamine Sensing Platform Based on FeMoSe₂-Graphene Oxide Nanocomposite

Detecting dopamine (DA) is vital for understanding neurodegenerative disease and the neurotransmitter-related biological process. Recently, electrochemical sensors have been rapidly developed in many fields due to their high sensitivity, great selectivity, and excellent stability. They are useful to detect and monitor dopamine. In this study, we have constructed a novel electrochemical sensor dependent on the mixing of FeMoSe 2 and graphene oxide (GO), and it was used for detecting dopamine. MoSe 2 presented the stacking of nanosheets, which provided larger surface areas and more active sites. GO was ultrathin-layered nanostructures, which made it disperse on MoSe 2 . Because of GO hybridization, the electrochemical activity of FeMoSe 2 has been enhanced. In addition, scanning electron microscopy, X-ray diffraction, Fourier transform infrared, and X-ray photoelectron spectroscopy techniques were made use of to characterize the surface morphology and structure of all prepared materials. We also used differential pulse voltammetry technique to assess the sensor’s range of detection (0.04–40 μM). Meanwhile, the sensor displayed the limit of detection of 2.22 nM (S/N = 3). Additionally, the constructed electrochemical sensor exhibited excellent repeatability, stability, and selectivity.