Factors associated with the presence and intensity of ongoing symptoms in Long COVID

Symptoms of anxiety were the strongest correlate of PASC-SPI, highlighting it as both a potential neuroinflammatory marker of PASC and a modifiable component of the illness. This emphasizes the need for comprehensive, whole person treatment strategies that integrate evidence-based interventions to address the multifaceted nature of PASC.

Authors

David Ring (ORCID: https://orcid.org/0000-0002-6506-4879)
Seung W. Choi (ORCID: https://orcid.org/0000-0003-4777-5420)
Teun Teunis (ORCID: https://orcid.org/0000-0001-5660-0695)
Niels Brinkman
W. Michael Brode

Institutions

University of Pittsburgh (US)
The University of Texas at Austin (US)

Publication Details

Journal: PLoS ONE
Published: 2025-04-23
DOI: https://doi.org/10.1371/journal.pone.0319874
Primary Topic: Long-Term Effects of COVID-19
Type: article
Field-Weighted Citation Impact: 0.00

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article

Factors associated with the presence and intensity of ongoing symptoms in Long COVID

David Ring, Seung W. Choi, Teun Teunis, Niels Brinkman et al.

Apr 23, 2025

PLoS ONE

Long-Term Effects of COVID-19

article

Factors associated with the presence and intensity of ongoing symptoms in Long COVID

David Ring, Seung W. Choi, Teun Teunis, Niels Brinkman, W. Michael Brode

April 23, 2025article en

Abstract

Symptoms of anxiety were the strongest correlate of PASC-SPI, highlighting it as both a potential neuroinflammatory marker of PASC and a modifiable component of the illness. This emphasizes the need for comprehensive, whole person treatment strategies that integrate evidence-based interventions to address the multifaceted nature of PASC.

PLoS ONEVol. 20(4)

University of Pittsburgh (US), The University of Texas at Austin (US)

Good health and well-being

Openalex Percentile: Top 86%

Long-Term Effects of COVID-19

DOI Open Access PDF OpenAlex

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