Insight into black phosphorus interactions with supported lipid bilayers
AFM imaging and force measurements revealed significant destabilization of the lipid bilayer, with a reduction in rupture force by more than half upon interaction with BP flakes. MD simulations corroborated these results, showing penetration and disruption of the lipid bilayer by BP. These findings enhance our understanding of nanomaterial-membrane interactions and demonstrate BP's potential for developing advanced nanomaterial-based drug delivery systems and antimicrobial therapies.
Authors
- Saffron J. Bryant (ORCID: https://orcid.org/0000-0002-7202-3004)
- Aaron Elbourne (ORCID: https://orcid.org/0000-0002-4472-4372)
- Gary Bryant (ORCID: https://orcid.org/0000-0001-5483-7592)
- Sumeet Walia (ORCID: https://orcid.org/0000-0002-3645-9847)
- Rowan Penman
- Rashad Kariuki (ORCID: https://orcid.org/0000-0002-2576-5179)
- Andrew J. Christofferson (ORCID: https://orcid.org/0000-0003-0904-6630)
- Kalpani A. Mirihana (ORCID: https://orcid.org/0000-0002-1108-9480)
- Shreehari Kodakkat (ORCID: https://orcid.org/0009-0007-3029-1186)
- Pierre H. A. Valliant
Institutions
- MIT University (MK)
- RMIT University (AU)
Publication Details
- Journal
- Journal of Colloid and Interface Science
- Published
- 2025-04-23
- DOI
- https://doi.org/10.1016/j.jcis.2025.137686
- Citations
- 2
- Primary Topic
- Lipid Membrane Structure and Behavior
- Type
- article
- Field-Weighted Citation Impact
- 1.61
Funders
- Australian Research Council