A novel antioxidant and anti-inflammatory carboxymethylcellulose/chitosan hydrogel loaded with cannabidiol promotes the healing of radiation-combined wound skin injury in the 60Co γ-irradiated mice
By integrating CBD into a CMC/CS-based hydrogel without using toxic crosslinkers, this study provides a novel, biomaterial-based, biocompatible approach for RW injury. These findings pave the way for future clinical application of CMC/CS3/CBD hydrogel in RW injury.
Authors
- Zhexin Ni (ORCID: https://orcid.org/0000-0002-9723-2398)
- Xiang Gao (ORCID: https://orcid.org/0000-0003-0699-0351)
- Zhijie Bai (ORCID: https://orcid.org/0000-0003-2231-1320)
- Xiongbing Zu (ORCID: https://orcid.org/0000-0002-6534-1493)
- Pan Shen (ORCID: https://orcid.org/0000-0001-8529-3727)
- Wei Zhou (ORCID: https://orcid.org/0000-0001-5116-9461)
- Chaoji Huangfu (ORCID: https://orcid.org/0000-0002-8650-7149)
- Yaolei Ma
- Ningning Wang (ORCID: https://orcid.org/0000-0002-1363-3101)
- Dezhi Sun (ORCID: https://orcid.org/0000-0002-0069-452X)
- Long Zhu
- Yangyi Hu (ORCID: https://orcid.org/0009-0001-0441-0571)
- Yue Gao
- Pengfei Zhang (ORCID: https://orcid.org/0000-0003-3306-4484)
Institutions
- Qinghai University (CN)
- Tianjin University of Traditional Chinese Medicine (CN)
- Beijing Electronic Science and Technology Institute (CN)
- Chinese PLA General Hospital (CN)
- Beijing Radiation Center (CN)
- Institute of Pharmacology (CZ)
Publication Details
- Journal
- Phytomedicine
- Published
- 2025-04-23
- DOI
- https://doi.org/10.1016/j.phymed.2025.156790
- Citations
- 6
- Primary Topic
- Wound Healing and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 6.16