Bacteriophage-embedded and coated alginate layers inhibit biofilm formation by clinical strains of <i>Klebsiella pneumoniae</i>
Phages vB_KpnA_GBH014 and vB_KpnM_GBH019 can both prevent and disrupt biofilms produced by clinical isolates of K. pneumoniae. Embedding and coating these phages into alginate produces an antibiofilm matrix which may have promise for coating medical devices or as a wound dressing.
Authors
- Hala R. Ali (ORCID: https://orcid.org/0000-0001-5879-2176)
- David Negus (ORCID: https://orcid.org/0000-0001-9047-4565)
- Carlos Valdivia
Institutions
- Universitat de València (ES)
- Institute for Integrative Systems Biology (ES)
- Animal Health Research Institute (TW)
- Nottingham Trent University (GB)
Publication Details
- Journal
- Journal of Applied Microbiology
- Published
- 2025-04-23
- DOI
- https://doi.org/10.1093/jambio/lxaf099
- Citations
- 4
- Primary Topic
- Bacteriophages and microbial interactions
- Type
- article
- Field-Weighted Citation Impact
- 6.87
Funders
- Consejo Superior de Investigaciones Científicas