A clinical trial evaluating feasibility and acceptability of a brain-computer interface for telerehabilitation in patients with stroke

This study serves as a proof of concept, showcasing the feasibility and acceptability of the proposed Tele BCI-FES system for rehabilitating the upper extremities of stroke survivors. While some participants demonstrated significant improvements in FMA-UE scores, these findings are not generalizable, as they were derived from a small-scale feasibility study. The results should be interpreted cautiously within the study's specific context. Additionally, the intervention was not compared to other therapeutic approaches, limiting conclusions regarding its relative effectiveness. To further validate the efficacy of the proposed Tele BCI-FES system, it is essential to conduct additional research with larger sample sizes and extended rehabilitation sessions. Moreover, future studies should include comparisons with other therapeutic approaches to better evaluate the relative effectiveness of this intervention. Trial registration This clinical study is registered at clinicaltrials.gov https://clinicaltrials.gov/study/NCT05215522 under the study identifier (NCT05215522) and registered with the ISRCTN registry https://doi.org/10.1186/ISRCTN42991002 (ISRCTN42991002).