Blood collection technique and processing impact the nucleosomes and complement contents of platelet products
Aphaeresis-PC can be better activated than BC-PC. BC-PC contains higher levels of nucleosomes and EA, most likely due to the presence of neutrophils in the BC. In addition, higher levels of complement activation products were observed in BC-PC.
Authors
- Thomas R. Klei (ORCID: https://orcid.org/0000-0002-2864-4073)
- Ido J. Bontekoe (ORCID: https://orcid.org/0000-0001-9103-7148)
- Yasmin E. S. de Wit (ORCID: https://orcid.org/0000-0002-0185-3916)
- Anja ten Brinke (ORCID: https://orcid.org/0000-0002-0135-7496)
- Sacha Zeerleder (ORCID: https://orcid.org/0000-0002-2290-2019)
- Rick van Andel
Institutions
- University of Bern (CH)
- University of Lucerne (CH)
- Sanquin (NL)
- Luzerner Kantonsspital (CH)
Publication Details
- Journal
- Vox Sanguinis
- Published
- 2025-04-22
- DOI
- https://doi.org/10.1111/vox.70031
- Primary Topic
- Blood transfusion and management
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Stichting Sanquin Bloedvoorziening