Plasticity of ventral tegmental area disturbance during abstinence after repeated amphetamine exposure: restoration by selective activation of group II metabotropic glutamate receptors
Thus, abstinence from repeated AMPH intake drives VTA activity from hypo-into hyperdopaminergic states, and both can be readjusted towards physiological levels via different members of group II mGluRs.
Authors
- Stefan Boehm (ORCID: https://orcid.org/0000-0002-0205-2459)
- Haydar Bulut (ORCID: https://orcid.org/0000-0003-0262-6296)
- Sophie Wieser
- Ornella Valenti (ORCID: https://orcid.org/0000-0003-3647-6046)
- Petra Scholze (ORCID: https://orcid.org/0000-0003-4984-6034)
- Katarzyna Anna Rekawek
Institutions
- Hochschule Campus Wien (AT)
- Medical University of Vienna (AT)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-04-23
- DOI
- https://doi.org/10.3389/fphar.2025.1534101
- Primary Topic
- Neuroscience and Neuropharmacology Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Austrian Science Fund